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November 18, 2024

PicoQuant to launch cutting-edge TCSPC unit at SPIE Photonics West 2025

The new TCSPC unit is built for applications demanding excellent time-resolution, precision, and multi-channel flexibility

PicoQuant is excited to announce the launch of a next-generation Time-Correlated Single Photon Counting (TCSPC) unit this January at SPIE Photonics West 2025 in San Francisco. This innovative addition to our portfolio of TCSPC and Time Tagging Electronics sets a new standard in advanced photonics research. Designed for applications requiring exceptional time-resolution, precision, and flexible multi-channel capabilities, the new unit is ideal for fields such as quantum communication and time-resolved spectroscopy. With its debut just around the corner, this game-changing TCSPC unit is set to unlock new possibilities in advanced photonics research.

Join us at booths 8511 and 3511 to witness the reveal firsthand!
SPIE Photonics West
January 25-30, 2025

Stay updated and visit the website of our new TCSPC unit >

PicoQuant to launch cutting-edge TCSPC unit at SPIE Photonics West 2025

September 10, 2024

Introducing NovaFLIM: Advanced analysis of images

The new software package is based on GPU-accelerated algorithms

Our new software NovaFLIM is designed for an efficient and multi-faceted analysis of FLIM, FLIM-FRET, and anisotropy imaging. It simplifies batch analysis of time-lapse, z-stack measurements with GPU-accelerated data processing. The software includes multi-exponential fitting, phasor plots, and pattern matching analysis increasing the confidence in the analysis and simplifying the application of time-resolved imaging in molecular cellular biology and in specific to liquid-liquid phase separation, cellular environment sensing, and cellular plant biology.

Read more on the NovaFLIM website >

Introducing NovaFLIM: Advanced analysis of images

July 4, 2024

FluoTime 300 spectrometer: Enhanced safety and precision

The high-performance instrument is now equipped with Class 1 laser safety and further new features

Our FluoTime 300 fluorescence lifetime spectrometer now features advanced enhancements, designed to elevate precision and safety in time-resolved spectroscopy. These improvements include a Class 1 laser option, new laser excitation capabilities, and the integration of the latest TCSPC electronics.

Press Release
FluoTime 300 spectrometer: Enhanced safety and precision

May 8, 2024

New PicoHarp 330: 4 channels. 4 more flexibility.

Unique flexibility broadens the scope of potential experiments

The PicoHarp 330 TCSPC and time tagging unit is now equipped with up to four detection channels and a dedicated sync channel with advanced channel configuration. The sync channel can be used as an additional detection channel if no synchronization signal is needed.

This enhancement not only broadens the scope of potential experiments but also significantly optimizes the efficiency of data collection in complex setups.

Key features include:

  • Enhanced Channel Configuration: The 4+1 channels allow researchers to conduct more complex and diverse experiments. This is especially beneficial in quantum optics experiments like Quantum Key Distribution (QKD), Quantum Entanglement and Bell Test Experiments.
  • Unmatched Low Jitter: Offering down to 2 ps RMS jitter, essential for accurate timing in QKD and photon correlation techniques.
  • Independet yet Synchronized Channels: Each channel operates independently but can synchronize with the others through a common sync channel, providing flexibility in experimental setups. If synchronization is not required, the sync input can serve as an additional detection channel, ideal for coincidence correlation or counting experiments with up to five channels.

Explore how the new PicoHarp 330 can transform your research with its cutting-edge technology designed to meet the demanding requirements of modern scientific exploration.

Read more on the product page >

New PicoHarp 330: 4 channels. 4 more flexibility.

April 18, 2024

New development enables rapid 3D FLIM imaging in living organoids

Combining single objective light-sheet microscopy with pulsed excitation and time-resolved SPAD array detection

Using a self-developed single objective light-sheet microscopy set-up, Valentin Dunsing-Eichenauer from Aix-Marseille Université & CNRS, Johan Hummert from PicoQuant, Ivan Michel Antolović from Pi Imaging Technology, and colleagues show lifetime-based multiplexing in 3D as well as time-lapse FLIM of mechanosensitive tension probes at record speed in living embryonic organoids. The set-up is based on pulsed excitation using a high power laser prototype and time-resolved detection on a newly available SPAD array detector.

Confocal FLIM is a popular tool for multiplexing and functional imaging of sensor fluorophores, but it is limited with regard to acquisition speed of large samples and live cell compatibility. Light-sheet microscopy, on the other hand, allows for fast and gentle imaging of large specimen. Combining both techniques opens new possibilities for fast volumetric FLIM.

Read the paper at bioRxiv >

New development enables rapid 3D FLIM imaging in living organoids